The 12th Annual Minnesota Neuromodulation Symposium is organized by the Institute for Engineering in Medicine (IEM) and MnDRIVE Brain Conditions. This symposium aims to bring together basic scientists, engineers, clinicians, industrial practitioners, and entrepreneurs to discuss the challenges and opportunities in neuromodulation. The event will feature plenary presentations by leaders in academia, industry, and government, along with poster presentations to foster idea exchange in this exciting field. The symposium, part of IEM Innovation Week, will be held immediately following the Design of Medical Devices Conference.